产品货号：
Z33825
中文名称：
SLP76/LCP2 Purified抗体
英文名称：
Anti-SLP76/LCP2 Purified Antibody (Clone#SLP-76/03)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SLP76/LCP2 Purified Antibody (Clone#SLP-76/03) |
| 指标别名 | LCP2;Lymphocyte cytosolic protein 2;SLP 76;SLP 76 tyrosine phosphoprotein;SLP76 |
| 克隆性 | Monoclonal |
| 检验物种 | pig,human,mouse |
| 应用范围 | WB,IHC |
| 基因名称 | LCP2 |
| 克隆号 | SLP-76/03 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | Bacterially expressed fusion protein representing amino acids 216-434 of human SLP76 with histidine tag.The monoclonal antibody reacts with SLP76,a 76kDa cytosolic adaptor protein that is involved in signaling of various hematopoietic cells,such as T cells,mast cells or neutrophils;in B cells,however,it is replaced by SLP65. |
| 计算分子量 | 60kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | SLP76 (SH2 domain-containing leukocyte protein of 76kDa) is a cytosolic adaptor protein which translocates to the plasma mambrane and is involved in multiple signaling pathways in T cells,mast cells,neutrophils and platelets;B cells express its analog SLP65/BLNK (B cell linker protein).SLP76 is phosphorylated by Syk-family and Tec-family tyrosine kinases and couples them to the phosphorylation and activation of PLC-gamma.Via Gads or Grb2,SLP76 also associates with LAT adaptor by involvement of SLP76 proline-rich region.The SH2 domain of SLP76 has been identified as the region involved in binding the serine/threonine kinase HPK1.HPK1 may act as both a positive and a negative regulator by promoting the Jnk-mitogen activated protein kinase (MAPK) pathway and inhibiting the pathway leading to AP-1 activation. |
| Uniprot ID | Q13094 |
| 基因名全称 | Lymphocyte cytosolic protein 2 |
| 蛋白名全称 | Lymphocyte cytosolic protein 2 |
| 推荐稀释比 | Immunohistochemistry (paraffin sections):10μg/mL;positive tissue:thymus |
相关搜索：SLP76/LCP2 Purified抗体，SLP76抗体，LCP2 Purified单抗